What ingredient in local anesthetic is used to neutralize the pH?

In local anesthetics, a buffer is included to help neutralize the pH of the solution. Local anesthetics typically have a low pH, which can cause discomfort upon injection and may hinder the effectiveness of the anesthetic. By incorporating a buffer, the formulation's pH is adjusted closer to that of the body's natural pH, facilitating better nerve block and reducing the stinging sensation during application.

If the pH is more neutral, the anesthetic agent is able to penetrate nerve membranes more effectively, leading to quicker onset and improved quality of anesthesia. This buffering action is crucial for enhancing patient comfort and achieving optimal dental outcomes during procedures requiring local anesthesia.